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Aspergillus niger Prolyl Endoprotease for Hydrogen–Deuterium Exchange Mass Spectrometry and Protein Structural Studies

[Image: see text] To monitor the structural integrity of therapeutic proteins, hydrogen–deuterium exchange mass spectrometry (HDX-MS) is increasingly utilized in the pharmaceutical industry. The successful outcome of HDX-MS analyses depends on the sample preparation conditions, which involve the rap...

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Bibliografiske detaljer
Udgivet i:Anal Chem
Main Authors: Tsiatsiani, Liana, Akeroyd, Michiel, Olsthoorn, Maurien, Heck, Albert J. R.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2017
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541327/
https://ncbi.nlm.nih.gov/pubmed/28657298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b01161
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