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The yeast EDC1 mRNA undergoes deadenylation-independent decapping stimulated by Not2p, Not4p, and Not5p

A major mechanism of eukaryotic mRNA degradation initiates with deadenylation followed by decapping and 5′ to 3′ degradation. We demonstrate that the yeast EDC1 mRNA, which encodes a protein that enhances decapping, has unique properties and is both protected from deadenylation and undergoes deadeny...

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Bibliografske podrobnosti
izdano v:EMBO J
Main Authors: Muhlrad, Denise, Parker, Roy
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2005
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC554118/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15706350/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600560
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