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The enhancer of decapping proteins, Edc1p and Edc2p, bind RNA and stimulate the activity of the decapping enzyme
A major pathway of eukaryotic mRNA turnover initiates with deadenylation, which allows a decapping reaction leading to 5′–3′ exonucleolytic degradation. A key control point in this pathway is the decapping of the mRNA. Two proteins, Edc1 and Edc2, were genetically identified previously as enhancers...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Copyright 2003 by RNA Society
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370390/ https://ncbi.nlm.nih.gov/pubmed/12554867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2171203 |
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