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Performance and in-house validation of a bioassay for the determination of beta1-autoantibodies found in patients with cardiomyopathy
BACKGROUND: Autoantibodies specific for the adrenergic beta1-receptor were identified to be an essential factor for the pathogenesis of dilated cardiomyopathy. For the detection of these autoantibodies, a bioassay was developed and has been used, measuring the positive chronotropic effect on spontan...
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| Publié dans: | Heliyon |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5541141/ https://ncbi.nlm.nih.gov/pubmed/28795160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2017.e00362 |
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