Doberman pinschers present autoimmunity associated with functional autoantibodies: A model to study the autoimmune background of human dilated cardiomyopathy

BACKGROUND: Autoimmunity associated with autoantibodies against the β1-adrenergic receptor (β1-AAB) is increasingly accepted as the driver of human dilated cardiomyopathy (DCM). Unfortunately, there is a lack of animal models to extend the knowledge about β1-AAB autoimmunity in DCM and to develop ap...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Wess, Gerhard, Wallukat, Gerd, Fritscher, Anna, Becker, Niels-Peter, Wenzel, Katrin, Müller, Johannes, Schimke, Ingolf
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611557/
https://ncbi.nlm.nih.gov/pubmed/31276517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214263
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