The aptamer BC 007 for treatment of dilated cardiomyopathy: evaluation in Doberman  Pinschers of efficacy and outcomes

AIMS: Aptamer BC 007, a 15‐mer single‐strand DNA oligonucleotide (5'‐GGTTGGTGTGGTTGG‐3'), was developed to neutralize functional autoantibodies that bind to the extracellular domains of G protein‐coupled receptors (GPCR‐AAB), leading to the modulation of receptor‐mediated signalling cascad...

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Bibliografiske detaljer
Udgivet i:ESC Heart Fail
Main Authors: Werner, Sabine, Wallukat, Gerd, Becker, Niels‐Peter, Wenzel, Katrin, Müller, Johannes, Schimke, Ingolf, Wess, Gerhard
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Original Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261533/
https://ncbi.nlm.nih.gov/pubmed/32212256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ehf2.12628
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