Connexin 43 is required for the maintenance of mitochondrial integrity in brown adipose tissue

We investigated the role of connexin 43 (Cx43) in maintaining the integrity of mitochondria in brown adipose tissue (BAT). The functional effects of Cx43 were evaluated using inducible, adipocyte-specific Cx43 knockout in mice (Gja1 (adipoq)KO) and by overexpression and knockdown of Cx43 in cultured...

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Publicado no:Sci Rep
Main Authors: Kim, Sang-Nam, Kwon, Hyun-Jung, Im, Seo-Woo, Son, Yeon-Ho, Akindehin, Seun, Jung, Young-Suk, Lee, Se Jeong, Rhyu, Im Joo, Kim, Il Yong, Seong, Je-Kyoung, Lee, Jinu, Yoo, Hee-Chan, Granneman, James G., Lee, Yun-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540980/
https://ncbi.nlm.nih.gov/pubmed/28769076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07658-y
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