Connexin 43 is required for the maintenance of mitochondrial integrity in brown adipose tissue

We investigated the role of connexin 43 (Cx43) in maintaining the integrity of mitochondria in brown adipose tissue (BAT). The functional effects of Cx43 were evaluated using inducible, adipocyte-specific Cx43 knockout in mice (Gja1 (adipoq)KO) and by overexpression and knockdown of Cx43 in cultured...

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Pubblicato in:Sci Rep
Autori principali: Kim, Sang-Nam, Kwon, Hyun-Jung, Im, Seo-Woo, Son, Yeon-Ho, Akindehin, Seun, Jung, Young-Suk, Lee, Se Jeong, Rhyu, Im Joo, Kim, Il Yong, Seong, Je-Kyoung, Lee, Jinu, Yoo, Hee-Chan, Granneman, James G., Lee, Yun-Hee
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540980/
https://ncbi.nlm.nih.gov/pubmed/28769076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07658-y
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