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Anti-inflammatory role of 15-lipoxygenase contributes to the maintenance of skin integrity in mice

15-lipoxygenase is involved in the generation of specialized pro-resolving lipid mediators that play essential roles in resolution and inflammatory responses. Here, we investigated anti-inflammatory role of Alox15 in skin homeostasis. We demonstrated that knockout (KO) of Alox15 led to hair loss and...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kim, Sang-Nam, Akindehin, Seun, Kwon, Hyun-Jung, Son, Yeon-Ho, Saha, Abhirup, Jung, Young-Suk, Seong, Je-Kyung, Lim, Kyung-Min, Sung, Jong-Hyuk, Maddipati, Krishna Rao, Lee, Yun-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995961/
https://ncbi.nlm.nih.gov/pubmed/29891910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27221-7
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