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Femtogram Level Sensitivity achieved by Surface Engineered Silica Nanoparticles in the Early Detection of HIV Infection

We have engineered streptavidin labelled Europium doped fluorescent silica nanoparticles which significantly increased sensitivity without compromising the specificity of the immunoassay. As a proof of concept, a time resolved fluorescence based sandwich immunoassay was developed to detect HIV-1 p24...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Chunduri, L. A. Avinash, Kurdekar, Aditya, Haleyurgirisetty, Mohan Kumar, Bulagonda, Eswarappa Pradeep, Kamisetti, Venkataramaniah, Hewlett, Indira K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540927/
https://ncbi.nlm.nih.gov/pubmed/28769052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07299-1
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