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Femtogram Level Sensitivity achieved by Surface Engineered Silica Nanoparticles in the Early Detection of HIV Infection

We have engineered streptavidin labelled Europium doped fluorescent silica nanoparticles which significantly increased sensitivity without compromising the specificity of the immunoassay. As a proof of concept, a time resolved fluorescence based sandwich immunoassay was developed to detect HIV-1 p24...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Rep
Κύριοι συγγραφείς: Chunduri, L. A. Avinash, Kurdekar, Aditya, Haleyurgirisetty, Mohan Kumar, Bulagonda, Eswarappa Pradeep, Kamisetti, Venkataramaniah, Hewlett, Indira K.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group UK 2017
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540927/
https://ncbi.nlm.nih.gov/pubmed/28769052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07299-1
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