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Interactions of β-Amyloid Peptide with Fibrinogen and Coagulation Factor XII may contribute to Alzheimer’s Disease

PURPOSE OF THE REVIEW: To review the evidence that the Alzheimer peptide β-amyloid (Aβ) interacts with the blood coagulation system and influences the pathophysiology of the disease. RECENT FINDINGS: That Aβ can interact with fibrinogen and blood coagulation Factor XII and trigger ischemia and infla...

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Detalhes bibliográficos
Publicado no:Curr Opin Hematol
Main Authors: Ahn, Hyung Jin, Chen, Zu-Lin, Zamolodchikov, Daria, Norris, Erin H., Strickland, Sidney
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540762/
https://ncbi.nlm.nih.gov/pubmed/28661939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000368
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