Fibrinogen and β-amyloid association alters thrombosis and fibrinolysis: a possible contributing factor to Alzheimer's disease

Alzheimer's disease (AD) is a neurodegenerative disorder in which vascular pathology plays an important role. Since the β-amyloid peptide (Aβ) is a critical factor in this disease, we examined its relationship to fibrin clot formation in AD. In vitro and in vivo experiments showed that fibrin c...

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Main Authors: Cortes-Canteli, Marta, Paul, Justin, Norris, Erin H., Bronstein, Robert, Ahn, Hyung Jin, Zamolodchikov, Daria, Bhuvanendran, Shivaprasad, Fenz, Katherine M., Strickland, Sidney
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895773/
https://ncbi.nlm.nih.gov/pubmed/20547128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.05.014
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