Naturally Generated Decoy of the Prostate Apoptosis Response-4 Protein Overcomes Therapy Resistance in Tumors

Primary tumors are often heterogeneous, composed of therapy-sensitive and emerging therapy-resistant cancer cells. Interestingly, treatment of therapy-sensitive tumors in heterogeneous tumor microenvironments results in apoptosis of therapy-resistant tumors. In this study, we identify a Par-4 amino-...

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Veröffentlicht in:Cancer Res
Hauptverfasser: Hebbar, Nikhil, Burikhanov, Ravshan, Shukla, Nidhi, Qiu, Shirley, Zhao, Yanming, Elenitoba-Johnson, Kojo S. J., Rangnekar, Vivek M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540761/
https://ncbi.nlm.nih.gov/pubmed/28625975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1970
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