The Microbiome Activates CD4 T-cell–mediated Immunity to Compensate for Increased Intestinal Permeability

BACKGROUND & AIMS: Despite a prominent association, chronic intestinal barrier loss is insufficient to induce disease in human subjects or experimental animals. We hypothesized that compensatory mucosal immune activation might protect individuals with increased intestinal permeability from disea...

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Gepubliceerd in:Cell Mol Gastroenterol Hepatol
Hoofdauteurs: Edelblum, Karen L., Sharon, Gil, Singh, Gurminder, Odenwald, Matthew A., Sailer, Anne, Cao, Severine, Ravens, Sarina, Thomsen, Irene, El Bissati, Kamal, McLeod, Rima, Dong, Chen, Gurbuxani, Sandeep, Prinz, Immo, Mazmanian, Sarkis K., Turner, Jerrold R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2017
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540699/
https://ncbi.nlm.nih.gov/pubmed/28795125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2017.06.001
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