The Microbiome Activates CD4 T-cell–mediated Immunity to Compensate for Increased Intestinal Permeability

BACKGROUND & AIMS: Despite a prominent association, chronic intestinal barrier loss is insufficient to induce disease in human subjects or experimental animals. We hypothesized that compensatory mucosal immune activation might protect individuals with increased intestinal permeability from disea...

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Veröffentlicht in:Cell Mol Gastroenterol Hepatol
Hauptverfasser: Edelblum, Karen L., Sharon, Gil, Singh, Gurminder, Odenwald, Matthew A., Sailer, Anne, Cao, Severine, Ravens, Sarina, Thomsen, Irene, El Bissati, Kamal, McLeod, Rima, Dong, Chen, Gurbuxani, Sandeep, Prinz, Immo, Mazmanian, Sarkis K., Turner, Jerrold R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2017
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540699/
https://ncbi.nlm.nih.gov/pubmed/28795125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2017.06.001
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