The Microbiome Activates CD4 T-cell–mediated Immunity to Compensate for Increased Intestinal Permeability

BACKGROUND & AIMS: Despite a prominent association, chronic intestinal barrier loss is insufficient to induce disease in human subjects or experimental animals. We hypothesized that compensatory mucosal immune activation might protect individuals with increased intestinal permeability from disea...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Edelblum, Karen L., Sharon, Gil, Singh, Gurminder, Odenwald, Matthew A., Sailer, Anne, Cao, Severine, Ravens, Sarina, Thomsen, Irene, El Bissati, Kamal, McLeod, Rima, Dong, Chen, Gurbuxani, Sandeep, Prinz, Immo, Mazmanian, Sarkis K., Turner, Jerrold R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540699/
https://ncbi.nlm.nih.gov/pubmed/28795125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2017.06.001
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