The Microbiome Activates CD4 T-cell–mediated Immunity to Compensate for Increased Intestinal Permeability

BACKGROUND & AIMS: Despite a prominent association, chronic intestinal barrier loss is insufficient to induce disease in human subjects or experimental animals. We hypothesized that compensatory mucosal immune activation might protect individuals with increased intestinal permeability from disea...

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Bibliografski detalji
Izdano u:Cell Mol Gastroenterol Hepatol
Glavni autori: Edelblum, Karen L., Sharon, Gil, Singh, Gurminder, Odenwald, Matthew A., Sailer, Anne, Cao, Severine, Ravens, Sarina, Thomsen, Irene, El Bissati, Kamal, McLeod, Rima, Dong, Chen, Gurbuxani, Sandeep, Prinz, Immo, Mazmanian, Sarkis K., Turner, Jerrold R.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2017
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540699/
https://ncbi.nlm.nih.gov/pubmed/28795125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2017.06.001
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