LMP1-mediated glycolysis induces myeloid-derived suppressor cell expansion in nasopharyngeal carcinoma

Myeloid-derived suppressor cells (MDSCs) are expanded in tumor microenvironments, including that of Epstein–Barr virus (EBV)-associated nasopharyngeal carcinoma (NPC). The link between MDSC expansion and EBV infection in NPC is unclear. Here, we show that EBV latent membrane protein 1 (LMP1) promote...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Cai, Ting-Ting, Ye, Shu-Biao, Liu, Yi-Na, He, Jia, Chen, Qiu-Yan, Mai, Hai-Qiang, Zhang, Chuan-Xia, Cui, Jun, Zhang, Xiao-Shi, Busson, Pierre, Zeng, Yi-Xin, Li, Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540616/
https://ncbi.nlm.nih.gov/pubmed/28732079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006503
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