Effects of liver-stage clearance by Primaquine on gametocyte carriage of Plasmodium vivax and P. falciparum

BACKGROUND: Primaquine (PQ) is the only currently licensed antimalarial that prevents Plasmodium vivax (Pv) relapses. It also clears mature P. falciparum (Pf) gametocytes, thereby reducing post-treatment transmission. Randomized PQ treatment in a treatment-to-reinfection cohort in Papua New Guinean...

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Vydáno v:PLoS Negl Trop Dis
Hlavní autoři: Wampfler, Rahel, Hofmann, Natalie E., Karl, Stephan, Betuela, Inoni, Kinboro, Benson, Lorry, Lina, Silkey, Mariabeth, Robinson, Leanne J., Mueller, Ivo, Felger, Ingrid
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540608/
https://ncbi.nlm.nih.gov/pubmed/28732068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005753
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