Strategies for Understanding and Reducing the Plasmodium vivax and Plasmodium ovale Hypnozoite Reservoir in Papua New Guinean Children: A Randomised Placebo-Controlled Trial and Mathematical Model

BACKGROUND: The undetectable hypnozoite reservoir for relapsing Plasmodium vivax and P. ovale malarias presents a major challenge for malaria control and elimination in endemic countries. This study aims to directly determine the contribution of relapses to the burden of P. vivax and P. ovale infect...

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Veröffentlicht in:PLoS Med
Hauptverfasser: Robinson, Leanne J., Wampfler, Rahel, Betuela, Inoni, Karl, Stephan, White, Michael T., Li Wai Suen, Connie S. N., Hofmann, Natalie E., Kinboro, Benson, Waltmann, Andreea, Brewster, Jessica, Lorry, Lina, Tarongka, Nandao, Samol, Lornah, Silkey, Mariabeth, Bassat, Quique, Siba, Peter M., Schofield, Louis, Felger, Ingrid, Mueller, Ivo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624431/
https://ncbi.nlm.nih.gov/pubmed/26505753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1001891
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