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Effects of liver-stage clearance by Primaquine on gametocyte carriage of Plasmodium vivax and P. falciparum.

Primaquine (PQ) is the only currently licensed antimalarial that prevents Plasmodium vivax (Pv) relapses. It also clears mature P. falciparum (Pf) gametocytes, thereby reducing post-treatment transmission. Randomized PQ treatment in a treatment-to-reinfection cohort in Papua New Guinean children per...

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Detalhes bibliográficos
Main Authors: Rahel Wampfler, Natalie E Hofmann, Stephan Karl, Inoni Betuela, Benson Kinboro, Lina Lorry, Mariabeth Silkey, Leanne J Robinson, Ivo Mueller, Ingrid Felger
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2017-07-01
Colecção:PLoS Neglected Tropical Diseases
Acesso em linha:http://europepmc.org/articles/PMC5540608?pdf=render
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