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Mismatch repair deficient hematopoietic stem cells are preleukemic stem cells

Whereas transformation events in hematopoietic malignancies may occur at different developmental stages, the initial mutation originates in hematopoietic stem cells (HSCs), creating a preleukemic stem cell (PLSC). Subsequent mutations at either stem cell or progenitor cell levels transform the PLSC...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Qing, Yulan, Gerson, Stanton L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540588/
https://ncbi.nlm.nih.gov/pubmed/28767666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182175
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