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Mismatch repair deficient hematopoietic stem cells are preleukemic stem cells
Whereas transformation events in hematopoietic malignancies may occur at different developmental stages, the initial mutation originates in hematopoietic stem cells (HSCs), creating a preleukemic stem cell (PLSC). Subsequent mutations at either stem cell or progenitor cell levels transform the PLSC...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5540588/ https://ncbi.nlm.nih.gov/pubmed/28767666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182175 |
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