Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition

The Toll-like receptor (TLR) family consists of phylogenetically conserved transmembrane proteins, which function as mediators of innate immunity for recognition of pathogen-derived ligands and subsequent cell activation via the Toll/IL-1R signal pathway. Here, we show that human TLR9 (hTLR9) expres...

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Detalhes bibliográficos
Main Authors: Bauer, Stefan, Kirschning, Carsten J., Häcker, Hans, Redecke, Vanessa, Hausmann, Susanne, Akira, Shizuo, Wagner, Hermann, Lipford, Grayson B.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55404/
https://ncbi.nlm.nih.gov/pubmed/11470918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161293498
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