Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition

The Toll-like receptor (TLR) family consists of phylogenetically conserved transmembrane proteins, which function as mediators of innate immunity for recognition of pathogen-derived ligands and subsequent cell activation via the Toll/IL-1R signal pathway. Here, we show that human TLR9 (hTLR9) expres...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Bauer, Stefan, Kirschning, Carsten J., Häcker, Hans, Redecke, Vanessa, Hausmann, Susanne, Akira, Shizuo, Wagner, Hermann, Lipford, Grayson B.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55404/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11470918/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.161293498
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