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A brain proteomic investigation of rapamycin effects in the Tsc1(+/−) mouse model
BACKGROUND: Tuberous sclerosis complex (TSC) is a rare monogenic disorder characterized by benign tumors in multiple organs as well as a high prevalence of epilepsy, intellectual disability and autism. TSC is caused by inactivating mutations in the TSC1 or TSC2 genes. Heterozygocity induces hyperact...
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| Publicado en: | Mol Autism |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5540199/ https://ncbi.nlm.nih.gov/pubmed/28775826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-017-0151-y |
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