Effects of antiepileptic drugs in a new TSC/mTOR‐dependent epilepsy mouse model

OBJECTIVE: An epilepsy mouse model for Tuberous Sclerosis Complex (TSC) was developed and validated to investigate the mechanisms underlying epileptogenesis. Furthermore, the possible antiepileptogenic properties of commonly used antiepileptic drugs (AEDs) and new compounds were assessed. METHODS: T...

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Veröffentlicht in:Ann Clin Transl Neurol
Hauptverfasser: Koene, Linda M. C., van Grondelle, Saskia E., Proietti Onori, Martina, Wallaard, Ilse, Kooijman, Nathalie H. R. M., van Oort, Annabel, Schreiber, Jadwiga, Elgersma, Ype
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6649373/
https://ncbi.nlm.nih.gov/pubmed/31353861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.50829
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