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β1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis
PURPOSE: Previous research showed that the absence of β1-integrin from the mouse lens after embryonic day (E) 13.5 (β1MLR10) leads to the perinatal apoptosis of lens epithelial cells (LECs) resulting in severe microphthalmia. This study focuses on elucidating the molecular connections between β1-int...
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| Published in: | Invest Ophthalmol Vis Sci |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Association for Research in Vision and Ophthalmology
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5539801/ https://ncbi.nlm.nih.gov/pubmed/28763805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-21721 |
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