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Conditional deletion of β1-integrin from the developing lens leads to loss of the lens epithelial phenotype

β1-integrins are cell surface receptors that participate in sensing the cell’s external environment. We used the Cre-lox system to delete β1-integrin in all lens cells as the lens vesicle transitions into the lens. Adult mice lacking β1-integrin in the lens are microopthalmic due to apoptosis of the...

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Detalhes bibliográficos
Main Authors: Simirskii, Vladimir N., Wang, Yan, Duncan, Melinda K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950782/
https://ncbi.nlm.nih.gov/pubmed/17493607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.04.004
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