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Conditional deletion of β1-integrin from the developing lens leads to loss of the lens epithelial phenotype
β1-integrins are cell surface receptors that participate in sensing the cell’s external environment. We used the Cre-lox system to delete β1-integrin in all lens cells as the lens vesicle transitions into the lens. Adult mice lacking β1-integrin in the lens are microopthalmic due to apoptosis of the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1950782/ https://ncbi.nlm.nih.gov/pubmed/17493607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.04.004 |
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