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Memory Upgrade: insights into primed adaptation by CRISPR-Cas immune systems
Recently, Künne et al. (2016) demonstrated that degradation products of Cas3 obtained during CRISPR interference fuel priming. In this issue of Molecular Cell, Xue et al. (2016) highlight the conformational changes in Cascade that underpin the priming process when interference is blocked.
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Mol Cell |
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| Κύριοι συγγραφείς: | , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5539784/ https://ncbi.nlm.nih.gov/pubmed/27863223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.11.008 |
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