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Memory Upgrade: insights into primed adaptation by CRISPR-Cas immune systems

Recently, Künne et al. (2016) demonstrated that degradation products of Cas3 obtained during CRISPR interference fuel priming. In this issue of Molecular Cell, Xue et al. (2016) highlight the conformational changes in Cascade that underpin the priming process when interference is blocked.

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell
Egile Nagusiak: Ramachandran, Anita, Bailey, Scott
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539784/
https://ncbi.nlm.nih.gov/pubmed/27863223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.11.008
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