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Memory Upgrade: insights into primed adaptation by CRISPR-Cas immune systems

Recently, Künne et al. (2016) demonstrated that degradation products of Cas3 obtained during CRISPR interference fuel priming. In this issue of Molecular Cell, Xue et al. (2016) highlight the conformational changes in Cascade that underpin the priming process when interference is blocked.

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Ramachandran, Anita, Bailey, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539784/
https://ncbi.nlm.nih.gov/pubmed/27863223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.11.008
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