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Automated generation of heuristics for biological sequence comparison

BACKGROUND: Exhaustive methods of sequence alignment are accurate but slow, whereas heuristic approaches run quickly, but their complexity makes them more difficult to implement. We introduce bounded sparse dynamic programming (BSDP) to allow rapid approximation to exhaustive alignment. This is used...

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Pubblicato in:BMC Bioinformatics
Autori principali: Slater, Guy St C, Birney, Ewan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2005
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553969/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15713233/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2105-6-31
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