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Pd-Catalyzed Conjunctive Cross-Coupling Between Grignard-Derived Boron "Ate" Complexes and C(sp(2)) Halides or Triflates: NaOTf as a Grignard Activator and Halide Scavenger

Catalytic enantioselective conjunctive cross-couplings that employ Grignard reagents are shown to furnish an array of non-racemic chiral organoboronic esters in an efficient and highly selective fashion. The utility of sodium triflate in facilitating this reaction is two-fold: it enables "ate&q...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Lovinger, Gabriel J., Aparece, Mark D., Morken, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539536/
https://ncbi.nlm.nih.gov/pubmed/28161943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b12663
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