Investigation of sphingosine kinase 1 in interferon responses during dengue virus infection

Dengue virus (DENV) regulates sphingosine kinase (SK)-1 activity and chemical inhibition of SK1 reduces DENV infection. In primary murine embryonic fibroblasts (pMEFs) lacking SK1 however, DENV infection is enhanced and this is associated with induction of normal levels of interferon beta (IFN-β) bu...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Clin Transl Immunology
Main Authors: Aloia, Amanda L, Calvert, Julie K, Clarke, Jennifer N, Davies, Lorena T, Helbig, Karla J, Pitson, Stuart M, Carr, Jillian M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539417/
https://ncbi.nlm.nih.gov/pubmed/28791126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cti.2017.32
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker