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Investigation of sphingosine kinase 1 in interferon responses during dengue virus infection
Dengue virus (DENV) regulates sphingosine kinase (SK)-1 activity and chemical inhibition of SK1 reduces DENV infection. In primary murine embryonic fibroblasts (pMEFs) lacking SK1 however, DENV infection is enhanced and this is associated with induction of normal levels of interferon beta (IFN-β) bu...
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| 出版年: | Clin Transl Immunology |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5539417/ https://ncbi.nlm.nih.gov/pubmed/28791126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cti.2017.32 |
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