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Structure of the C-terminal domain of TRADD reveals a novel fold in the death domain superfamily

The TNFR1-associated death domain protein (TRADD) is an intracellular adaptor protein involved in various signaling pathways, such as antiapoptosis. Its C-terminal death domain (DD) is responsible for binding other DD-containing proteins including the p75 neurotrophin receptor (p75(NTR)). Here we pr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Ning, Yuan, Wensu, Fan, Jing-Song, Lin, Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539145/
https://ncbi.nlm.nih.gov/pubmed/28765645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07348-9
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