Simultaneous determination of hydrophilic and lipophilic constituents in herbal medicines using directly-coupled reversed-phase and hydrophilic interaction liquid chromatography-tandem mass spectrometry

Limitations in the separation ability of conventional liquid chromatography system remains a challenge in developing a versatile method for simultaneously determining both hydrophilic and lipophilic constituents in herbal medicines (HMs). To measure compounds covering a broad polarity span in HMs, w...

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Udgivet i:Sci Rep
Main Authors: Sun, Wan-Yang, Lu, Qin-Wei, Gao, Hao, Tong, Ling, Li, Dong-Xiang, Zhou, Zheng-Qun, Jiang, Zheng-Jin, Sun, Henry, Bi, Kai-Shun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539142/
https://ncbi.nlm.nih.gov/pubmed/28765547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07087-x
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