Tandem Mass Tag Labeling Facilitates Reversed-Phase Liquid Chromatography-Mass Spectrometry Analysis of Hydrophilic Phosphopeptides

Protein phosphorylation is a critical post-translational modification (PTM). Despite recent technological advances in reversed-phase liquid chromatography (RPLC)-mass spectrometry (MS)-based proteomics, comprehensive phosphoproteomic coverage in complex biological systems remains challenging, especi...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Tsai, Chia-Feng, Smith, Jeffrey S., Krajewski, Krzysztof, Zhao, Rui, Moghieb, Ahmed M., Nicora, Carrie D., Xiong, Xinyu, Moore, Ronald J., Liu, Tao, Smith, Richard D., Jacobs, Jon M., Rajagopal, Sudarshan, Shi, Tujin
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197904/
https://ncbi.nlm.nih.gov/pubmed/31418558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b01814
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