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Simultaneous determination of ribonucleoside and deoxyribonucleoside triphosphates in biological samples by hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry

Information about the intracellular concentration of dNTPs and NTPs is important for studies of the mechanisms of DNA replication and repair, but the low concentration of dNTPs and their chemical similarity to NTPs present a challenge for their measurement. Here, we describe a new rapid and sensitiv...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Kong, Ziqing, Jia, Shaodong, Chabes, Anna Lena, Appelblad, Patrik, Lundmark, Richard, Moritz, Thomas, Chabes, Andrei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009580/
https://ncbi.nlm.nih.gov/pubmed/29554314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky203
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