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Simultaneous determination of ribonucleoside and deoxyribonucleoside triphosphates in biological samples by hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry

Information about the intracellular concentration of dNTPs and NTPs is important for studies of the mechanisms of DNA replication and repair, but the low concentration of dNTPs and their chemical similarity to NTPs present a challenge for their measurement. Here, we describe a new rapid and sensitiv...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Kong, Ziqing, Jia, Shaodong, Chabes, Anna Lena, Appelblad, Patrik, Lundmark, Richard, Moritz, Thomas, Chabes, Andrei
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009580/
https://ncbi.nlm.nih.gov/pubmed/29554314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky203
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