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Simultaneous determination of ribonucleoside and deoxyribonucleoside triphosphates in biological samples by hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry

Information about the intracellular concentration of dNTPs and NTPs is important for studies of the mechanisms of DNA replication and repair, but the low concentration of dNTPs and their chemical similarity to NTPs present a challenge for their measurement. Here, we describe a new rapid and sensitiv...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Kong, Ziqing, Jia, Shaodong, Chabes, Anna Lena, Appelblad, Patrik, Lundmark, Richard, Moritz, Thomas, Chabes, Andrei
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009580/
https://ncbi.nlm.nih.gov/pubmed/29554314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky203
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