Nebivolol Desensitizes Myofilaments of a Hypertrophic Cardiomyopathy Mouse Model

Background: Hypertrophic cardiomyopathy (HCM) patients often present with diastolic dysfunction and a normal to supranormal systolic function. To counteract this hypercontractility, guideline therapies advocate treatment with beta-adrenoceptor and Ca(2+) channel blockers. One well established pathom...

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Publicat a:Front Physiol
Autors principals: Stücker, Sabrina, Kresin, Nico, Carrier, Lucie, Friedrich, Felix W.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539082/
https://ncbi.nlm.nih.gov/pubmed/28824454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00558
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