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Radiolabeling optimization and characterization of (68)Ga labeled DOTA–polyamido-amine dendrimer conjugate – Animal biodistribution and PET imaging results
The present study describes the optimization of (68)Ga radiolabeling with PAMAM dendrimer–DOTA conjugate. A conjugate (PAMAM–DOTA) concentration of 11.69 µM, provided best radiolabeling efficiency of more than 93.0% at pH 4.0, incubation time of 30.0 min and reaction temperature ranging between 90 a...
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| 出版年: | Appl Radiat Isot |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5538890/ https://ncbi.nlm.nih.gov/pubmed/26232562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apradiso.2015.07.021 |
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