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Fmoc-Sec(Xan)-OH: Synthesis and Utility of Fmoc Selenocysteine SPPS Derivatives with Acid-Labile Sidechain Protection

We report here the synthesis of the first Selenocysteine SPPS derivatives which bear TFA-labile sidechain protecting groups. New compounds Fmoc-Sec(Xan) and Fmoc-Sec(Trt) are presented as useful and practical alternatives to the traditional Fmoc-Sec derivatives currently available to the peptide che...

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Vydáno v:J Pept Sci
Hlavní autor: Flemer, Stevenson
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538775/
https://ncbi.nlm.nih.gov/pubmed/25504629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psc.2723
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