SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination

Stimulation of cells with TNFα leads to the formation of the TNF-R1 signaling complex (TNF-RSC) to mediate downstream cellular fate decision. Activation of the TNF-RSC is modulated by different types of ubiquitination and may lead to cell death, including apoptosis and necroptosis, in both RIPK1-dep...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Wei, Ran, Xu, Lily Wen, Liu, Jianping, Li, Yanxia, Zhang, Pei, Shan, Bing, Lu, Xiaojuan, Qian, Lihui, Wu, Zheming, Dong, Kangyun, Zhu, Hong, Pan, Lifeng, Yuan, Junying, Pan, Heling
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538438/
https://ncbi.nlm.nih.gov/pubmed/28701375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.299776.117
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