Neat1 is a p53-inducible lincRNA essential for transformation suppression

The p53 gene is mutated in over half of all cancers, reflecting its critical role as a tumor suppressor. Although p53 is a transcriptional activator that induces myriad target genes, those p53-inducible genes most critical for tumor suppression remain elusive. Here, we leveraged p53 ChIP-seq (chroma...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Genes Dev
Hlavní autoři: Mello, Stephano S., Sinow, Carolyn, Raj, Nitin, Mazur, Pawel K., Bieging-Rolett, Kathryn, Broz, Daniela Kenzelmann, Imam, Jamie F. Conklin, Vogel, Hannes, Wood, Laura D., Sage, Julien, Hirose, Tetsuro, Nakagawa, Shinichi, Rinn, John, Attardi, Laura D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538433/
https://ncbi.nlm.nih.gov/pubmed/28698299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.284661.116
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky