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Treatment-Induced Mutagenesis and Selective Pressures Sculpt Cancer Evolution

Despite the great progress in our understanding of the molecular basis of human cancer, the heterogeneity of individual tumors and the evolutionary pressures imposed by therapy have hampered our ability to effectively eradicate and control this disease. How, therefore, do cancers evolve under the se...

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Pubblicato in:Cold Spring Harb Perspect Med
Autori principali: Venkatesan, Subramanian, Swanton, Charles, Taylor, Barry S., Costello, Joseph F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538404/
https://ncbi.nlm.nih.gov/pubmed/28289245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026617
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