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Treatment-Induced Mutagenesis and Selective Pressures Sculpt Cancer Evolution
Despite the great progress in our understanding of the molecular basis of human cancer, the heterogeneity of individual tumors and the evolutionary pressures imposed by therapy have hampered our ability to effectively eradicate and control this disease. How, therefore, do cancers evolve under the se...
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| 發表在: | Cold Spring Harb Perspect Med |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5538404/ https://ncbi.nlm.nih.gov/pubmed/28289245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026617 |
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