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Selective Pressures on Human Cancer Genes along the Evolution of Mammals

Cancer is a disease driven by both somatic mutations that increase survival and proliferation of cell lineages and the evolution of genes associated with cancer risk in populations. Several genes associated with cancer in humans, hereafter cancer genes, show evidence of germline positive selection a...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Vicens, Alberto, Posada, David
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316132/
https://ncbi.nlm.nih.gov/pubmed/30487452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9120582
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