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Selective Pressures on Human Cancer Genes along the Evolution of Mammals

Cancer is a disease driven by both somatic mutations that increase survival and proliferation of cell lineages and the evolution of genes associated with cancer risk in populations. Several genes associated with cancer in humans, hereafter cancer genes, show evidence of germline positive selection a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genes (Basel)
Prif Awduron: Vicens, Alberto, Posada, David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316132/
https://ncbi.nlm.nih.gov/pubmed/30487452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9120582
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