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Treatment-Induced Mutagenesis and Selective Pressures Sculpt Cancer Evolution

Despite the great progress in our understanding of the molecular basis of human cancer, the heterogeneity of individual tumors and the evolutionary pressures imposed by therapy have hampered our ability to effectively eradicate and control this disease. How, therefore, do cancers evolve under the se...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Med
Main Authors: Venkatesan, Subramanian, Swanton, Charles, Taylor, Barry S., Costello, Joseph F.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538404/
https://ncbi.nlm.nih.gov/pubmed/28289245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026617
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