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S-Nitrosomycothiol Reductase and Mycothiol Are Required for Survival Under Aldehyde Stress and Biofilm Formation in Mycobacterium smegmatis

We show that Mycobacterium smegmatis mutants disrupted in mscR, coding for a dual function S-nitrosomycothiol reductase and formaldehyde dehydrogenase, and mshC, coding for a mycothiol ligase and lacking mycothiol (MSH), are more susceptible to S-nitrosoglutathione (GSNO) and aldehydes than wild typ...

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Bibliografski detalji
Izdano u:IUBMB Life
Glavni autori: Vargas, Derek, Hageman, Samantha, Gulati, Megha, Nobile, Clarissa J., Rawat, Mamta
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538257/
https://ncbi.nlm.nih.gov/pubmed/27321674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.1524
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