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Impaired activity of adherens junctions contributes to endothelial dilator dysfunction in ageing rat arteries

KEY POINTS: Ageing‐induced endothelial dysfunction contributes to organ dysfunction and progression of cardiovascular disease. VE‐cadherin clustering at adherens junctions promotes protective endothelial functions, including endothelium‐dependent dilatation. Ageing increased internalization and degr...

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Detalles Bibliográficos
Publicado en:J Physiol
Main Authors: Chang, Fumin, Flavahan, Sheila, Flavahan, Nicholas A.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538197/
https://ncbi.nlm.nih.gov/pubmed/28561330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP274189
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